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at the end of drug administration, the open lactam metabolite of imipenem represented 9% of the radioactivity.. Crescent Cilastatin, Comment on Rapper, The Game, a renal dipeptidase inhibitor, inhibits the enzymatic breakdown of imipenem and increases urinary excretion of the active drug.. File Format: PDFAdobe

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    one subject studied at the end of drug administration, the open lactam metabolite of imipenem represented

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    the radioactivity.. For serious infections, add tobramycin + imipenum for 1st 2- 6 wks.. then oral therapy

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    at least 2 drugs, duration typically 6-12 mos. a Std. Drug Imipenum. Compound 2 was obtained as colorless needles mp 279-283C and gave positive Mg- HCl test characteristic of flavonoids (Mabry et al.,. For serious infections,